Estradiol Valerate

 

Brand: Delestrogen

Application: Menopause

 

Pharmaceutical forms of estradiol valerate

  • Tablets, solution for injection, topical gel

 

 

Estradiol Valerate Drug Information

Dosage and method of taking estradiol valerate

Contraindications to the use of estradiol valerate

Taking estradiol valerate during pregnancy and lactation

The effect of estradiol valerate on driving and operating machinery

Drug Interactions Estradiol Valerate

Special warnings and precautions while taking estradiol valerate

Side effects of estradiol valerate

Overdose of estradiol valerate (drug poisoning)

Storage conditions of estradiol valerate

 

 

Estradiol Valerate Drug Information

The symptoms of menopause are due to a lack of estrogen in the body; Estradiol valerate is a female hormone (estrogen) that helps reduce menopausal symptoms in women (such as hot flashes, vaginal dryness). Estradiol valerate may also be prescribed to women who are unable to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure), and men with prostate cancer.

 

Dosage and method of taking estradiol valerate

  • Read the package leaflet carefully before starting treatment with estradiol valerate. This brochure will help you to get comprehensive information about the drug and its possible side effects.
  • Consider the dose and type of estradiol valerate (tablets, solution for injection, topical gel) prescribed by your doctor; Use the medicine exactly as your doctor advised. Injectable estradiol valerate is usually given for 4 weeks, but sometimes it is only given for a short time, about 1-2 weeks, to treat prostate cancer.
  • Take the medicine regularly and at a set time so that you do not forget it.

 

Contraindications to the use of estradiol valerate

  • Note the expiration date of estradiol valerate and do not take it if it has expired.
  • Never give estradiol valerate to another person, even if you have the same symptoms.
  • Check for drug interactions with estradiol valerate, and if you are taking a drug that interacts with this drug, talk to your doctor about using your medications.g

 

Taking estradiol valerate during pregnancy and lactation

Never use this medicine during pregnancy and lactation. Medications, especially those that affect female hormones, can have devastating effects on the fetus or yourself.

 

The effect of estradiol valerate on driving and operating machinery

Estradiol valerate can cause headaches and dizziness, be sure to be careful before driving or operating machinery.

 

Drug Interactions Estradiol Valerate

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some drugs interfere with the function of estradiol valerate. These drugs include: aromatase inhibitors (such as anastasol, letrozole), tranexamic acid, toremifene, raloxifene, spemifene (ospemifene), fulrantrant.

Estradiol valerate may interfere with some tests (metirapone test) and may affect the results of these specific laboratory tests. Tell your doctor or nurse before taking any tests that you are taking any medication.

 

Special warnings and precautions while taking estradiol valerate

Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking estradiol valerate:

  • If you have a history of heart disease or stroke.
  • If your blood pressure is high.
  • If you have a history of unusual vaginal bleeding or problems with the uterus, such as fibroids, endometriosis, or endometrial hyperplasia (thickening of the uterine wall).
  • If you or a close family member has a blood clot problem in your blood vessels.
  • If you have breast cancer or any lumps in your breast, or if close family members have ever had breast cancer.
  • If you have any liver problems.
  • If you have a history of depression.
  • If you are pregnant or breastfeeding your baby.
  • If your blood prolactin level is high (hyperprolactinemia).
  • If you or a family member has high blood fats.
  • If you have problems during pregnancy such as severe itching and blistering of the skin, jaundice or any involuntary muscle movements.
  • If you have any conditions such as diabetes mellitus, gallstones, migraines, inflammatory bowel disease, lupus erythematosus (SLE) or porphyria.
  • If you have a history of an allergic reaction to a drug.
  • If you are currently taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor's prescription, such as herbal medicines and complementary medicines.

 

Side effects of estradiol valerate

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking the medicine. In case of persistent side effects, the physician should be informed:

  • Feeling sick and nauseous: Eat simple, low-fat, spice-free meals. Take the tablets after meals.
  • Headache: Ask your doctor to prescribe a suitable painkiller. See your doctor if you have an unusual, long-lasting headache.
  • Bloating, weight change, breast tenderness, stomach cramps, bloating, swelling, changes in libido, mood swings, leg spasms: See a doctor if these symptoms bother you.

Important Note: If you have any of the following symptoms, do not continue to take the medicine and see a doctor immediately:

  • Sudden chest pain
  • Menstrual bleeding or spotting
  • Sudden shortness of breath (or bloody cough)
  • Swelling or pain in the leg
  • Change in vision
  • Difficulty speaking
  • Excessive sweating
  • Unexpected severe headache

Consult your doctor if you have any other symptoms that you feel may be due to the use of estradiol valerate.

 

Overdose of estradiol valerate (drug poisoning)

  • Do not take more estradiol valerate than your doctor prescribes.
  • If you feel that someone has drug poisoning and you have symptoms such as severe nausea, unusual vaginal bleeding, shortness of breath or fainting (fainting), call the emergency room right away.

 

Storage conditions of estradiol valerate

  • Keep the medicine out of the reach of children.
  • Store the medicine in a cool, dry place away from heat and direct sunlight.
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