Indometacin

 

Brand: Indomethacin

Application: Relieves pain and inflammation

 

Pharmaceutical forms of indomethacin

  • Tablets, capsules, suppositories

 

 

 

Indomethacin Drug Information

Dosage and method of taking indomethacin

Contraindications Indomethacin

Indomethacin during pregnancy and lactation

The effect of indomethacin on driving and working with machines

Drug Interactions Indomethacin

Special warnings and precautions while taking indomethacin

Side effects of indomethacin

Indomethacin overdose (drug poisoning)

Storage conditions of indomethacin

 

 

 

Indomethacin Drug Information

Anti-inflammatory painkillers such as indomethacin are sometimes called nonsteroidal anti-inflammatory drugs (NSAIDs) or simply "anti-inflammatory drugs". Indomethacin is used to treat rheumatoid arthritis pain, pain due to heavy menstrual bleeding, and back pain. Indomethacin relieves pain and inflammation.

Indomethacin is known to inhibit cyclo-oxygenase enzymes. It works by blocking the action of cyclooxygenase enzymes. Cyclooxygenase enzymes are involved in the production of chemicals that stimulate the response to the disease, and by blocking the action of cyclooxygenase enzymes, the stimulants are not released. As a result, by blocking the effect of the COX enzyme, the symptoms of pain and inflammation in arthritis are reduced.

 

Dosage and method of taking indomethacin

  • Read the package leaflet carefully before starting treatment with indomethacin. This brochure will help you to get comprehensive information about the drug and its possible side effects.
  • The dose and amount of indomethacin varies from person to person; Use the medicine exactly as your doctor advised.
  • Take indomethacin with food or after a snack to avoid indigestion.
  • If you forget to take your daily dose of indomethacin at the right time but soon forget to take it; But if you remember when the next dose is near the hour, do not take the missed dose. You should not take two doses of the medicine together because of the missed dose.

 

Contraindications Indomethacin

  • Note the expiration date of indomethacin and do not take it if it has expired.
  • Never give indomethacin to another person, even if you have the same symptoms.
  • Check for drug interactions with indomethacin, and if you are taking a drug that interacts with this drug, talk to your doctor about using your medications.

 

Indomethacin during pregnancy and lactation

During pregnancy and lactation, you should not use the drug arbitrarily without consulting your doctor. Medications can have devastating effects on the fetus or on yourself.

 

The effect of indomethacin on driving and working with machines

Indomethacin may make you dizzy or drowsy, so make sure you are alert before driving or operating machinery.

 

Drug Interactions Indomethacin

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some medications that may interact with indomethacin include aliskiren, ACE inhibitors (such as captopril), lisinopril, angiotensin II receptor blockers (such as vosartan), and losartan (losartan). Cidofovir, corticosteroids (such as prednisone), lithium, methotrexate, and diuretic pills or "water pills" such as furosemide.

Check labels on all your medicines, especially painkillers or antipyretics (NSAIDs such as celecoxib, aspirin, ibuprofen, ketorolac, and naproxen, because their ingredients are similar). To indomethacin and may exacerbate the side effects of this drug. If your doctor prescribes low-dose aspirin (usually 81-325 mg per day) to prevent a heart attack or stroke, you should definitely take this medicine. Be sure to talk to your pharmacist about taking this medicine with other medicines. consult.

Indomethacin may increase the risk of bleeding if used with other medicines that cause bleeding. These include: Antiplatelet drugs such as clopidogrel, "blood thinners" such as dabigatran / enoxaparin / warfarin.

Indomethacin may interfere with certain laboratory tests, causing test results to be erroneous. Tell your doctor or nurse that you have used this medicine before the test.

 

Special warnings and precautions while taking indomethacin

Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking indomethacin:

  • If you have asthma or any allergic disorder.
  • If you have ever had a stomach ulcer or duodenal ulcer.
  • If you have inflammatory bowel disease such as Crohn's disease or ulcerative colitis.
  • If you decide to have a baby, if you are pregnant or if you are breast-feeding.
  • If you have kidney or liver problems.
  • If you have heart problems or vascular disorders or if you have poor blood circulation.
  • If you have high blood pressure.
  • If you are over 65 years old.
  • If you are a smoker.
  • If you have epilepsy or another brain health problem.
  • If your blood sugar and cholesterol levels are high.
  • If you have an unknown blood disorder called porphyria.
  • If you have ever had a blood clot problem.
  • If you have connective tissue diseases such as systemic lupus erythematosus (an inflammatory disease also called lupus or SLE).
  • If you are currently taking certain medications. These include all available medicines, whether prescribed or used by your doctor, such as herbal medicines and supplements.
  • If you have ever been allergic to a particular drug.

 

Side effects of indomethacin

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking the medicine. In case of persistent side effects, the physician should be informed:

  • Indigestion, heartburn, digestive problems: Remember to take the medicine with food or a glass of milk. If these problems persist, talk to your doctor.
  • Feeling sick and nauseous: Eat simple foods and plenty of water.
  • Diarrhea and constipation: Drink plenty of water to replenish lost water.
  • Drowsiness and dizziness: Avoid driving and working with tools.

Important Note: If you experience any of the following unusual but serious symptoms, stop taking indomethacin and call your doctor right away for advice:

• If you have any breathing problems such as wheezing, shortness of breath.

• If you have any signs of an allergic reaction such as swelling around the mouth or face or itchy pimples.

• If you have black or bloody stools or vomit blood or have abdominal pain.

Consult your doctor if you have any other symptoms that you feel are due to the use of indomethacin.

 

Indomethacin overdose (drug poisoning)

  • Do not take more indomethacin than your doctor prescribes.
  • If you feel that someone has been poisoned and you have symptoms such as severe stomach pain, vomiting, severe drowsiness, shortness of breath, fainting, and weakness (fainting), call the emergency room right away.

 

Storage conditions of indomethacin

  • Keep the medicine out of the reach of children.
  • Keep the medicine in a cool, dry place away from heat and direct sunlight.
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