Isoniazid

Isoniazid

 

Brand: Rifinah, Voractive, Rifater

Application: TB

 

 

 

Isoniazid drug information

Contraindications Isoniazid

Isoniazid drug interactions

Tips to consider before taking isoniazid

Possible side effects of isoniazid

How to store isoniazid

 

 

 

 

Isoniazid drug information

Medication Information: Isoniazid is used to treat tuberculosis. Tuberculosis is a bacterial infection that mainly affects the lungs but can affect other parts of the body as well. This infection can be treated with a 6-month course of medication. Several drugs must be used to treat tuberculosis. Isoniazid is just one of these drugs.

Isoniazid is usually given as a combination of two, three, or four pills. These brands are called Rifinah (isoniazid with rifampin), Rifater (isoniazid with rifampin and pyrazinamide) and Voractive (isoniazid with rifampin, pyrazinamide and ethambutol). Each of these brands may be prescribed at different stages of the disease. The use of combination drugs reduces the frequency of drug use.

Although isoniazid is an effective drug, it can sometimes damage peripheral nerves (numbness in the hands and feet). If there is a risk to the patient, the doctor will use a vitamin peroxidine supplement for prevention.

 

Contraindications Isoniazid

  • Pay attention to the expiration date of the medicine and do not take it if the medicine in your hand has expired.
  • Never give the medicine to anyone else, even if you have the same symptoms.
  • Do not take more than the dose prescribed by your doctor.
  • Check for drug interactions and be sure to tell your doctor what other medications you are taking.

 

Isoniazid drug interactions

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some of the drugs that may interact with isoniazid include acetaminophen, azole specific antifungals (itraconazole, ketoconazole), carbamazepine, disulfiram, MAO inhibitors (isocarboxazid, linzolid, phenylbelline, methylcellulose, phenylcellulose, methylcellulose. , Tranylcypromine), phenytoin, antidepressants (such as fluoxetine, sertraline), theophylline and valproic acid.

Isoniazid may interfere with certain laboratory tests (including urine glucose testing) and cause erroneous results. Before testing, inform all laboratory personnel and physicians that you have used this medicine.

 

Tips to consider before taking isoniazid

Some medications can not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed. Therefore, it is best for your doctor to be aware of the following before taking isoniazid:

  • If you are pregnant or breast-feeding. Although isoniazid has not caused any side effects during pregnancy, it is important for your doctor to know if you may need a supplement.
  • If you have kidney or liver disease.
  • If you have epilepsy or diabetes.
  • If you have a mental illness such as psychosis.
  • If you are addicted to alcohol.
  • If you are HIV positive.
  • If you have a low stabilizer. In these cases, the body may not be able to break down isoniazid well, so the chances of side effects are high.
  • If you have porphyria blood disease.
  • If you are currently taking certain medications. These include all available medicines, whether prescribed or used by your doctor, such as herbal medicines and supplements.
  • If you have ever been allergic to any medication.

 

Possible side effects of isoniazid

All medications, along with their positive effects, can cause unwanted side effects in the body. However, these complications do not occur in all people. Over time, your body will adjust to the new medicine and these symptoms will go away, but if the following symptoms persist or become painful, consult your doctor.

  • Murmuring, muscle weakness: Talk to your doctor about these as soon as possible.

Important Note: Isoniazid can cause liver problems in some cases. These symptoms include persistent nausea, weakness, and jaundice (yellowing of the skin and whites of the eyes). If these symptoms occur, see a doctor immediately.

Talk to your doctor if you have any other symptoms that you feel may be caused by isoniazid.

 

How to store isoniazid

  • Keep all medicines out of the reach of children.
  • Keep the medicine in a cool, dry place away from heat and direct sunlight.
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