Liver function test 37 weeks pregnant

 

Liver function test 37 weeks pregnant

 

Some women experience functional liver function tests during pregnancy, meaning that their liver enzymes change. Women with chronic liver disease and liver cirrhosis are more likely to lose their fetuses than other women.

In the following, we will talk more about the disorders of liver function tests in the weeks of pregnancy

And we will say what factors in pregnancy cause liver problems and impaired liver function test?

Before enumerating and explaining the problem factors, it is better to know what the purpose of liver function test is.

 

What is liver functional test?

What are the symptoms of liver dysfunction?

Causes of hepatic dysfunction test in pregnancy

Which women are most likely to develop AFLP?

Time of AFLP

What Happens During Pregnancy Fatty Liver?

AFLP symptoms

How is AFLP diagnosed? 

How is AFLP treated?

What are the complications of AFLP?

Is it possible to prevent AFLP?

What women are most likely to get Help Syndrome?

What are the symptoms of Help Syndrome?

How is Help Syndrome diagnosed?

Treatment of Help Syndrome

Background symptoms of preeclampsia

Symptoms of preeclampsia

Time of onset of preeclampsia

Diagnosis of preeclampsia

What is pregnancy cholestasis?

 

 

What is liver functional test?

They are a set of tests used to diagnose and monitor liver problems

Liver enzyme tests include:

  • AST; damage to liver cells causes large amounts of this substance to be released into the bloodstream
  • ALT; increases in liver and muscle injuries
  • Alkp; in the bile ducts of the liver and bone problems, this enzyme is elevated in the blood.

Other liver function tests include:

  • Bilirubin (increased blood levels of this substance are associated with jaundice, the liver clears this substance of blood)
  • Albumin (a very important protein for the health of the body that is produced by the liver)

There are other types of materials that can be measured, which will be explained in detail in later articles.

 

 

What are the symptoms of liver dysfunction?

These disorders are often accompanied by the following symptoms:

  • Weakness and fatigue
  • Weight loss
  • Yellowing of the skin
  • Yellow eyes
  • Stool lightening
  • Darkening of the urine
  • Nausea
  • Vomit
  • Abdominal pain
  • Accumulation of fluid in the abdomen
  • Easy bruising
  • Abnormal bleeding

 

 

Causes of hepatic dysfunction test in pregnancy

Three percent of pregnancies are associated with impaired liver function testing. The following are the causes of liver dysfunction in pregnancy weeks.

 

  • Fatty liver of pregnancy:

This relatively rare complication is called AFLP for short; it occurs only in human pregnancy.

 

 

Which women are most likely to develop AFLP?

  • Multiple pregnancies
  • First pregnancy
  • Thin
  • Pregnancy of male fetus
  • Women who have a genetic disorder themselves or their fetus

 

 

Time of AFLP

The doctor diagnoses this disorder in late pregnancy and before delivery, but it is interesting to say that it is even possible to get it right after delivery.

This complication typically occurs between the thirty and thirty-eighth weeks of pregnancy, so impaired liver function tests in the thirty-seventh week of pregnancy may indicate this complication

It may occur early in pregnancy, around the 18th week, or within four days of delivery.

 

 

What Happens During Pregnancy Fatty Liver?

Hepatic impairment or liver failure that occurs following AFLA can cause many problems for both mother and fetus. Death may occur if not diagnosed and treated

 

 

AFLP symptoms

  • Nausea
  • Vomit
  • Malaise
  • Headache
  • Fatigue
  • Jaundice in severe cases
  • Yellow eyes in severe cases
  • Confusion
  •  

Many of these symptoms overlap with normal illnesses. So if you are pregnant and have these symptoms, be sure to tell your doctor and midwife.

 

 

How is AFLP diagnosed?

History and careful examination of clinical signs along with blood tests and liver function tests that show the status of liver enzymes and bilirubin are used for diagnosis in pregnancy.

The definitive diagnosis of fatty liver is a liver biopsy, but this biopsy is not performed during pregnancy.

In addition to measuring liver function tests with a normal blood sample, your doctor may also use ultrasound and CT scans.

 

 

 How is AFLP treated?

As soon as AFLP is diagnosed, the fetus should be removed from your body as soon as possible. After delivery, the risk to the mother and fetus decreases; you may need to stay in the AES for a while. In most cases, liver function and liver function tests return to normal after few weeks.

 

 

What are the complications of AFLP?

Both you and your fetus are at serious risk of death

You may suffer from:

  • Liver failure
  • Kidney failure
  • Severe bleeding
  • Very severe infections

Without early detection, AFLP is very dangerous and deadly

 

 

Is it possible to prevent AFLP?

Acute fatty liver in pregnancy is neither preventable nor predictable.

We emphasize that if you see the mentioned symptoms, it is necessary to see a doctor immediately

As soon as AFLP is diagnosed, fetal delirium should be performed as soon as possible to reduce the risk to the mother and fetus.

There are two important complications in pregnancy that are very serious and dangerous and are unfortunately very often confused with acute fatty liver in pregnancy.

  1. Hellp syndrome:

It is one of the most serious complications in pregnancy that can be very fatal if not diagnosed and treated late.

 

 

What women are most likely to get Hellp Syndrome?

  • Pregnancy after the age of thirty-five
  • Obesity of a pregnant woman
  • History of previous pregnancy poisoning
  • History of maternal hypertension
  • Diabetes
  • History of previous pregnancy poisoning
  • Previous preeclampsia

 

 

What are the symptoms of Hellp Syndrome?

  • Feeling sick and tired
  • Nausea
  • Vomit
  • Headache
  • Swelling, especially swelling of the hands and face
  • Sudden and severe weight gain
  • Blurred vision, blindness, or other changes in vision
  • Shoulder pain
  • Pain when you take a deep breath.

In rare cases, the patient experiences seizures and confusion.

 

These symptoms indicate a worsening of Help Syndrome and you should see a doctor without wasting time

The most common time of onset of Help Syndrome is around the time of pregnancy

And it may occur up to the first forty hours of labor

Even up to the first seven days after delivery, there is a possibility of this syndrome, which can lead to seizures and maternal death.

 

 

How is Hellp Syndrome diagnosed?

 

  • Measurement of liver enzymes:

Liver function testing is defective in this syndrome

In other words, one of the causes of impaired liver function testing in the 37th week of pregnancy is Help syndrome.

  • Blood cell and platelet count test:
  • Urine protein measurement (in Hellp we have urinary protein excretion syndrome)
  • test
  • blood pressure

 

 

Treatment of Hellp Syndrome

As soon as Hellp Syndrome is diagnosed, delivery should be done as soon as possible.

 

  1. Pre-eclampsia:

Five percent of pregnancies develop this high-risk complication

 

 

Background symptoms of preeclampsia

  • Obesity mother
  • Gestational age less than twenty years and more than thirty years
  • Twin and multiple pregnancies
  • Maternal previous blood pressure
  • History of preeclampsia in previous pregnancies
  • Coagulation disorders
  • Autoimmune diseases such as lupus
  • Family history of preeclampsia mother, sister and aunt

 

 

Symptoms of preeclampsia

  • Severe, persistent and prolonged headaches
  • vision changes, blurred vision, seeing light points in the visual field, sensitivity to light and temporary loss of vision
  • nausea and vomiting
  • Pain or tenderness in the upper right side of the abdomen
  • Severe swelling of the face, around the eyes and hands
  • Sudden weight gain for example, one and a half kilograms, is unusual in a week.

 

 

Time of onset of preeclampsia

It often occurs from the thirty-seventh week onwards. But it can also occur twenty-four to forty-eight hours after delivery

Sometimes it can happen in the second half of pregnancy

 

 

Diagnosis of preeclampsia

Preeclampsia has no special symptoms in the early stages, so it is necessary to be under the constant supervision of your midwife or doctor during pregnancy.

Systolic blood pressure of a pregnant woman more than one hundred and forty millimeters of mercury or diastolic pressure above ninety millimeters of mercury is considered pathological.

It is not possible to prevent or predict the occurrence of preeclampsia, but if preeclampsia occurs before the 30th week of pregnancy, it is more likely to recur in the next pregnancies.

Changes in liver enzymes or impaired liver function tests at 37 weeks of gestation can raise suspicion of preeclampsia and hellp syndrome.

 

 

What is pregnancy cholestasis?

Decreased gallbladder emptying is common in pregnancy and late pregnancy. Hormonal changes in pregnant women both increase bile production and slow down gallbladder movements to empty the gallbladder. Totally, bile stasis occurs in the gallbladder or cholestasis occurs. It stays in the gallbladder for a long time

Pregnancy cholestasis can be associated with severe itching in late pregnancy

Also, if stasis and thickening of the bile causes the production of gallstones, this stone can block the bile ducts out of the bag and cause severe pain in the upper and right abdomen, especially after eating a heavy and fatty meal.

The pain extends to the right shoulder or back. This condition is called cholecystitis. If an acute attack of cholecystitis occurs, liver function tests may be impaired. In Acute gestational cholecystitis that does not respond to other treatments, laparoscopic cholecystectomy (removal of the gallbladder) is the treatment of choice.

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