Mefenamic acid

 

General English name: Mefenamic acid

Brand: Ponstan

Application: Reduces pain and inflammation in adults and children over 12 years

 

 

 

 

 

Pharmacological forms of mefenamic acid

Pharmacological information of mefenamic acid

Dosage and method of taking mefenamic acid

Contraindications Mefenamic acid

Mefenamic acid consumption during pregnancy and lactation

The effect of mefenamic acid on driving and working with machines

Mefenamic acid drug interactions

Special warnings and precautions while taking mefenamic acid

Side effects of mefenamic acid

Mefenamic acid overdose (drug poisoning)

Storage conditions of mefenamic acid

 

 

 

 

 

 

 

 

 Pharmacological forms of mefenamic acid

Tablets, capsules, oral liquid medicine (syrup)

 

 Pharmacological information of mefenamic acid

Anti-inflammatory painkillers such as mefenamic acid are sometimes called non-steroidal anti-inflammatory drugs (NSAIDs) or just "anti-inflammatory drugs". Mefenamic acid is used to treat rheumatoid arthritis pain, pain due to heavy menstrual bleeding, and postoperative pain. Mefenamic acid relieves pain and inflammation.

Mefenamic acid is known to inhibit cyclo-oxygenase enzymes. It works by blocking the action of cyclooxygenase enzymes. Cyclooxygenase enzymes are involved in the production of chemicals that stimulate the response to the disease, and by blocking the action of cyclooxygenase enzymes, the stimulants are not released. As a result, by blocking the effect of the COX enzyme, the symptoms of pain and inflammation in arthritis are reduced.

 

Dosage and method of taking mefenamic acid

  • Read the package leaflet carefully before starting treatment with mefenamic acid. This brochure will help you to get comprehensive information about the drug and its possible side effects.
  • The dose and amount of mefenamic acid varies from person to person; Use the medicine exactly as your doctor advised. The usual dose of mefenamic acid is 500 mg per day (two 250 mg capsules or one 500 mg tablet) and is preferably taken in the morning and evening.
  • Eat mefenamic acid with food to avoid indigestion.
  • If you forget to take your daily dose of mefenamic acid at the right time but soon forget to take it; But if you remember when the next dose is near the hour, do not take the missed dose. You should not take two doses of the medicine together because of the missed dose.

 

Contraindications Mefenamic acid

Note the expiration date of the mefenamic acid medicine and do not take it if the medicine in your hand has expired.

Never give mefenamic acid to another person, even if you have the same symptoms.

Check for mefenamic acid drug interactions, and if you are using a drug that interacts with this drug, talk to your doctor about using your medications.

 

Mefenamic acid consumption during pregnancy and lactation

During pregnancy and lactation, you should not use the drug arbitrarily and without consulting your doctor. Medications can have devastating effects on the fetus or on yourself.

 

The effect of mefenamic acid on driving and working with machines

Mefenamic acid may confuse or make you drowsy, make sure you are alert before driving or operating machinery.

 

 Mefenamic acid drug interactions

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some medications that may interact with mefenamic acid include aliskiren, ACE inhibitors (such as captopril), lisinopril, angiotensin II receptor blockers (such as vosartan, losartan, vosartan) ), Lithium, fluconazole, ketorolac, methotrexate, and diuretic pills or "water pills" such as furosemide.

Check the labels on all your medicines, especially painkillers or fever (nonsteroidal anti-inflammatory drugs (NSAIDs) such as celecoxib, aspirin, ibuprofen, ketorolac, and naproxen, because their ingredients are similar. It is mefenamic acid and may aggravate the side effects of this drug. If your doctor prescribes low-dose aspirin (usually 81-325 mg per day) to prevent a heart attack or stroke, you should definitely take this medicine. Be sure to talk to your pharmacist about taking this medicine with other medicines. consult.

Mefenamic acid may increase the risk of bleeding if used with other medicines that cause bleeding. These include: Antiplatelet drugs such as clopidogrel, "blood thinners" such as dabigatran / enoxaparin / warfarin.

Mefenamic acid may interfere with certain laboratory tests (urine bile test) and cause the test results to be erroneous. Tell your doctor or nurse that you have used this medicine before the test.

 

Special warnings and precautions while taking mefenamic acid

Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking mefenamic acid:

  • If you have asthma or any allergic disorder.
  • If you have ever had a stomach ulcer or duodenal ulcer.
  • If you have inflammatory bowel disease such as Crohn's disease or ulcerative colitis.
  • If you decide to have a baby, if you are pregnant or if you are breast-feeding.
  • If you have kidney or liver problems.
  • If you have heart problems or vascular disorders or if you have poor blood circulation.
  • If you have high blood pressure.
  • If you have epilepsy.
  • If your blood sugar and cholesterol levels are high.
  • If you have an unknown blood disorder called porphyria.
  • If you have ever had a blood clot problem.
  • If you have connective tissue diseases such as systemic lupus erythematosus (an inflammatory disease also called lupus or SLE).
  • If you are currently taking certain medications. These include all available medicines, whether prescribed or used by your doctor, such as herbal medicines and supplements.
  • If you have ever been allergic to a particular drug.

 

Side effects of mefenamic acid

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away after a short time of taking the medicine. In case of persistent side effects, the physician should be informed:

Indigestion, heartburn, digestive problems: Remember to take the medicine with food or a glass of milk. If these problems persist, talk to your doctor.

Feeling sick and nauseous: Eat simple foods and plenty of water.

Diarrhea: Drink plenty of water to replenish lost water.

Skin rash: Do not continue to take medication and see a doctor.

Mouth sores: Tell your doctor if this complication bothers you.

Important Note: If you experience any of the following unusual but serious symptoms, stop taking mefenamic acid and contact your doctor immediately for advice:

• If you have any breathing problems such as wheezing, shortness of breath.

• If you have any signs of an allergic reaction such as swelling around the mouth or face or itchy pimples.

• If you have black or bloody stools or vomit blood or have abdominal pain.

Consult your doctor if you have any other symptoms that you feel may be due to mefenamic acid.

 

Mefenamic acid overdose (drug poisoning)

Do not take mefenamic acid more than the dose prescribed by your doctor.

If you feel that someone has been poisoned and you have symptoms such as severe stomach pain, vomiting, severe drowsiness, shortness of breath, fainting, and weakness (fainting), call the emergency room right away.

 

Storage conditions of mefenamic acid

Keep the medicine out of the reach of children.

Keep the medicine in a cool, dry place away from heat and direct sunlight.

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