Meperidine-Pethidine

 

General English Name: Meperidine | Pethidine

Brand: Demerol®

Application: Pain relief

 

 

Pharmaceutical forms of pethidine

Pethidine Drug Information

Dosage and method of pethidine use

Contraindications to the use of pethidine

Use of pethidine during pregnancy and lactation

The effect of pethidine on driving and working with machines

Drug Interactions Pethidine

Special warnings and precautions while taking pethidine

Side effects of pethidine

Overdose of pethidine (drug poisoning)

Storage conditions of pethidine

 

 

 

Pharmaceutical forms of pethidine

Tablets, injectable vials

 

 Pethidine Drug Information

Strong narcotics are drugs used to treat severe pain. Pethidine is a potent drug used to treat severe pain such as labor (in the past). This medicine affects your nervous system and brain and reduces your pain. Pethidine is usually given as an injection, it is also available as a pill, but it is rarely given.

 

Dosage and method of pethidine use

A vial of pethidine is usually given to you by a nurse in a hospital to relieve pain, and the dose and amount of the injection is determined by your doctor.

If this medicine is prescribed for you as a pill, ask your doctor how much to take and do not change the dose.

Pethidine can be addictive, use it only for the period prescribed for you.

 

Contraindications to the use of pethidine

  • Pay attention to the expiration date of the pethidine medicine and do not take it if the medicine in your hand has expired.
  • Never give pethidine to another person, even if you have the same symptoms.
  • Check for drug interactions, and if you are taking a drug that interacts with this medication, talk to your doctor about using your medications.

 

Use of pethidine during pregnancy and lactation

During pregnancy and lactation, you should not use the drug arbitrarily without consulting your doctor. Medications can have devastating effects on the fetus or on yourself.

 

The effect of pethidine on driving and working with machines

Pethidine causes drowsiness. Avoid driving and operating machinery as long as it is effective in your body. It takes a full day for the effect of this medicine to leave your body.

 

 Drug Interactions Pethidine

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some medications that may interact with pethidine include certain painkillers (such as pentazocine, nalbuphine, butorphanol), and naltrexone.

Pethidine interacts severely with MAO inhibitors, which may even lead to death. Do not use phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine. Most MAO inhibitors should not be used until 2 weeks before and after starting pethidine.

If you take other drugs that increase serotonin, your risk of developing serotonin syndrome or toxicity increases. Examples of these medications include: MDMA "ecstasy", St. John's wort, certain antidepressants (including SSRIs such as fluoxetine / paroxetine, SNRIs such as duloxetine). duloxetine) / venlafaxine).

The specific medications listed below can increase the risk of side effects of pethidine (such as slow breathing, severe drowsiness, and dizziness) if medications such as alcohol, sleeping pills, or anxiety medications (such as lorazepam, diazepam) are used. , Zolpidem, antihistamines (such as diphenhydramine and cetirizine), muscle relaxants, and analgesics and painkillers (such as codeine). Tell your doctor or pharmacist.

Check the labels on all your medicines (such as allergies or cough and cold medicines) because some of them are made up of substances that cause drowsiness. Ask your pharmacist how to use them so that you can use them safely.

Other drugs that can affect the removal of pethidine from your body and thus affect its function include: Azole antifungals (such as ketoconazole), macrolide antibiotics (such as erythromycin), rifampins (such as rifabutin), ritonavir , Drugs used to treat seizures (such as carbamazepine, phenytoin).

 

Special warnings and precautions while taking pethidine

Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking pethidine:

  • If you are pregnant or planning to become pregnant, or if you are breast-feeding.
  • If you have any liver or kidney disease.
  • If you have prostate problems or any problems with urination.
  • If you have any respiratory problems such as asthma or chronic obstructive pulmonary disease (COPD).
  • If you have low blood pressure.
  • If you have any thyroid or adrenal problems.
  • If you have epilepsy.
  • If you have a bile duct problem.
  • If you have had constipation for more than a week or have an inflammatory bowel problem.
  • If you have a condition called myasthenia gravis (muscle weakness).
  • If you have recently had a severe head injury.
  • If you are addicted to drugs and alcohol.
  • If you are taking other medicines. These include all available medicines, whether prescribed or used by your doctor, such as herbal medicines and supplements.
  • If you are allergic to any medicine.

 

Side effects of pethidine

All medications can cause side effects. But many consumers also do not experience any side effects. Some side effects go away shortly after taking pethidine. In case of persistent side effects, the doctor should be informed:

Feeling dizzy, drowsy and weak: In these situations, avoid driving and working with tools.

Feeling sick (nausea), heartburn: Eat small, spicy meals.

Dry mouth: Look for sugar-free gum.

Constipation: Drink plenty of fluids and fiber.

Headache, hot flashes, sweating, hives, difficulty urinating, shortness of breath: Tell your doctor if any of these things bother you.

 

Overdose of pethidine (drug poisoning)

Do not take more than the dose prescribed by your doctor.

If you feel that someone has been poisoned and you have symptoms such as severe dizziness, coma, shortness of breath, fainting and weakness (fainting), call the emergency room immediately.

 

Storage conditions of pethidine

If you need to keep a pethidine vial at home, ask your doctor or nurse how to store a pethidine vial.

Keep the medicine out of the reach of children.

Store the medicine in a cool, dry place away from heat and direct sunlight.

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