General English name: Paroxetine

Brand: Seroxat

Application: Depression - Anxiety Disorders - Obsessive Compulsive Disorder (OCD)




Paroxetine Pharmacological Information

Contraindications to paroxetine

Paroxetine drug interaction

Tips to consider before taking paroxetine

Possible side effects of paroxetine

How to store paroxetine




Paroxetine Pharmacological Information

Medication Information: Paroxetine is prescribed to treat depression, anxiety disorders, and mental disorders. Depression can occur for no apparent reason or as a result of social issues, loss of loved ones, or various illnesses. Anxiety is the most common symptom in anxiety disorder. Panic disorder, anxiety disorder, social panic and post-traumatic stress disorder are all anxiety disorders.

Brain cells called neurons produce a variety of chemicals that can stimulate other neurons. This leads to the production of electrical pulses that carry out brain functions. Serotonin is a chemical in the brain. Once produced, this chemical stimulates neurons and is then reabsorbed into neurons. Serotonin reuptake inhibitors, such as paroxetine, increase the amount of serotonin available to the brain. Balancing chemicals helps reduce depression and anxiety.


Contraindications to paroxetine

Pay attention to the expiration date of the paroxetine drug and do not take it if the medicine in your hand has expired.

Never give paroxetine to anyone else, even if you have the same symptoms.

Do not take more than the dose prescribed by Paroxetine.

Check for paroxetine drug interactions and be sure to tell your doctor what other medications you are taking.


Paroxetine drug interaction

It may alter the function of the medication and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter medicines and herbal products) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some medications that may interact with paroxetine include thioridazine, medications that can cause bleeding or bruising (including antiplatelet drugs such as clopidogrel, nonsteroidal anti-inflammatory drugs such as ibuprofen, ibuprofen). Such as warfarin.

Paroxetine can slow down the elimination of some drugs from the body and affect their function. Examples of affected drugs include atomoxetine, phenothiazine, pimozide, risperidone, tamoxifen, tetrabenazine, antiarrhythmic drugs (such as propafenone, flecainide, quinidine), and TCA antidepressants such as amitriptyline, dc.

Paroxetine can cause serious drug interactions with MAO inhibitors, which can even lead to death. Do not use phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine. Most MAO inhibitors should not be used until 2 weeks before starting paroxetine.

Check the labels on all your medicines (such as allergies or cough and cold medicines) because some of them contain substances that cause drowsiness or increase the risk of bleeding. Ask your doctor about using them so you can use them safely.

Aspirin, if taken with paroxetine, can increase the risk of bleeding. However, if your doctor prescribes low-dose aspirin (usually 325-81 mg per day) to prevent a stroke or heart attack, you should continue to take it unless your doctor tells you to stop taking it. Give aspirin. Consult your pharmacist for more details.

If you are taking medicines that cause drowsiness, tell your doctor or pharmacist, including: alcohol, antihistamines (such as cetirizine, diphenhydramine), sleeping pills or anxiety medications (such as alprazolam), alp Diazepam, zolpidem, muscle relaxants, and analgesics and painkillers (such as codeine).

If you take serotonin-boosting drugs in combination with paroxetine, your risk of serotonin toxicity increases. Tell your doctor if you are using these referees. These include: street medications such as MDMA / "ecstasy", St. John's wort, specific antidepressants (including SSRIs such as fluoxetine / citalopram, SNRIs such as venlafaxine). Keep in mind that the risk of serotonin toxicity syndrome increases when you increase the dose of these drugs or start using these drugs.

Paroxetine may interfere with certain tests (including brain scans for Parkinson's disease) and cause erroneous results. Talk to your lab staff about using this medicine before testing.


Tips to consider before taking paroxetine

Some medications are not suitable for people with certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking paroxetine:

  • If you are pregnant or planning to become pregnant or breast-feeding your baby.
  • If your blood pressure is high.
  • If you have diabetes.
  • If you have a history of high mood (such as bipolar disorder mania).
  • If you have any liver or kidney problems.
  • If you have a heart problem.
  • If you have glaucoma (increased eye pressure).
  • If you have ever had a seizure or epilepsy.
  • If you have a blood disorder or a history of bleeding.
  • If you have ever had electroconvulsive therapy (ECT).
  • If you have used an antidepressant such as a mono-oxidase inhibitor (MAOI) in the last two weeks.
  • If you are taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor's prescription, such as herbal medicines and complementary medicines.
  • If you have a history of an allergic reaction to a drug.


Possible side effects of paroxetine

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away after a short time of taking the medicine. In case of persistent side effects, the physician should be informed:

  • Nausea, diarrhea and constipation: Eat simple foods and drink several glasses of water daily.
  • Blurred vision, lack of concentration, dizziness, drowsiness: Avoid driving and working with tools in these situations.
  • Dry mouth: Look for sugar-free gum.
  • Headache: Ask your doctor to prescribe a suitable painkiller.
  • Mood swings, anger, restlessness and tremors: These symptoms usually go away in the first few days of taking the medicine. But if any of these things bother you, talk to your doctor.
  • Sweating, yawning, sleep problems, unusual sleep patterns, weight gain, loss of sexual power: Tell your doctor if any of these things bother you.
  • Important Note: Some people taking this medicine may be allergic to it. See your doctor as soon as possible if you notice any swelling around the mouth, breathing problems, or skin rashes.
  • Consult your doctor if you have any other symptoms that you feel are due to the use of paroxetine.


How to store paroxetine

Keep all medicines out of the reach of children.

Keep the medicine in a cool, dry place away from heat and direct sunlight.

This can be consumed for up to a month after opening the lid of the ceroxate syrup. Do not use it after this period.

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