Penicillamine

 

General English name: Penicillamine

Brand: Distamine

Application: Autoimmune diseases such as rheumatoid arthritis and some metabolic disorders such as Wilson's disease and cystinuria

 

 

 

 

Penicillamine Drug Information

Contraindications to penicillamine

Penicillamine drug interaction

Tips to consider before taking penicillamine:

Possible side effects of penicillamine

How to store penicillamine

 

 

 

 

 

Penicillamine Drug Information

Medication Information: Rheumatoid arthritis is an autoimmune disease. The immune system produces a protein called an antibody to trap bacteria and viruses, but in autoimmune diseases, the immune system produces antibodies against the body's tissues. In patients with rheumatoid arthritis, antibodies are produced against the tissues around the joints, which causes inflammation, pain, and swelling around the joints. Penicillamine belongs to a group of drugs called disease-modifying anti-rheumatic drugs (DMARDs), which are prescribed to suppress inflammation and prevent tissue invasion, and reduce the damaging effects of rheumatoid arthritis on the joints.

Penicillamine is also used to treat some metabolic disorders such as Wilson's disease and cystinuria. In Wilson's disease, the drug binds to copper metal ions in the body to form compounds that are easily removed from the body. Penicillamine for the treatment of cystinuria reduces the concentration of urinary cystine. This drug prevents the formation of crystals that make up kidney or bladder stones.

 

Contraindications to penicillamine

  • Pay attention to the expiration date of the penicillamine drug and do not take it if the expiration date on your medicine has expired.
  • Never give penicillamine to anyone else, even if you have the same symptoms.
  • Do not take more than the prescribed dose of penicillamine.
  • Check for penicillin interactions and be sure to tell your doctor what other medications you are taking.
  • Avoid taking zinc and iron medications two hours before taking penicillamine.

 

Penicillamine drug interaction

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some medications that may interact with this drug include digoxin, malaria medications (such as chloroquine), phenylbutazone, bone marrow-lowering drugs (such as azathioprine, cancer chemotherapy, trimethoprim). / Sulfamethoxazole).

 

Tips to consider before taking penicillamine:

Some medications are not suitable for people with certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking penicillamine:

  • If you are pregnant or breast-feeding.
  • If you have any kidney disease.
  • If you have lupus erythematosus (an autoimmune disease that causes inflammation).
  • If you have a history of an allergic reaction to a drug.
  • If you are currently taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor's prescription, such as herbal medicines and complementary medicines.

 

Possible side effects of penicillamine

All medications can cause side effects. But many consumers also do not experience any side effects. In case of persistent side effects, the physician should be informed:

  • Feeling sick, loss of appetite, diarrhea, headache, dizziness, changes in vision, loss of sense of taste (taste)
  • Important Note: You may experience certain side effects from blood disorders caused by taking penicillamine. See your doctor right away if you have any of these symptoms:
  • Sore throat with fever or cold-like symptoms
  • Oral ulcers
  • Skin rash
  • Unusual bruising or bleeding, such as blood in the urine
  • Feeling unwell
  • Talk to your doctor if you have any symptoms that you think may be due to penicillamine.

 

How to store penicillamine

Keep the medicine out of the reach of children.

Store the medicine in a cool, dry place away from heat and direct sunlight.

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