Posaconazole

 

 

 

General English name: Posaconazole

Brand: Noxafil

Application: Fungal infection in adults

 

 

 

 

Dosage forms of posaconazole

Posaconazole Drug Information

Dosage and method of taking posaconazole

Contraindications to posaconazole

Posaconazole during pregnancy and lactation

The effect of posaconazole on driving and working with machines

Posaconazole drug interactions

Special warnings and precautions while taking posaconazole

Side effects of posaconazole

Overdose of posaconazole (drug poisoning)

Storage conditions of posaconazole

 

 

 

Dosage forms of posaconazole

Tablets, liquid medicine

 

Posaconazole Drug Information

Fungal infections can sometimes develop inside the body, and these infections can be serious. If your immune system is not working properly, for example, if you are undergoing chemotherapy or if you have a disease such as AIDS, you are at higher risk for a fungal infection. Posaconazole is used to treat serious fungal infections that have not been treated with other antifungal drugs. Posaconazole prevents infection by stopping the growth of the fungus.

 

Dosage and method of taking posaconazole

Read the package leaflet carefully before starting treatment with this medicine. This brochure will help you to get comprehensive information about the drug and its possible side effects.

  • The dose and amount of posaconazole varies from person to person; Use the medicine exactly as your doctor advised. Usually in the first few days you should take 300 mg (3 tablets) of posaconazole tablets twice a day and then reduce the dose to 300 mg once a day. The dosage of liquid medicine also varies between 1-4 times a day.
  • Reduce mg once a day. The dosage of liquid medicine also varies between 1-4 times a day.
  • You can take posaconazole before or after a meal, but you should take the liquid medicine after a meal.
  • You should take posaconazole for a full period. Do not stop taking the medicine without your doctor's permission.
  • If you forget to take your daily dose at the right time but soon forget, take the medicine; But if you remember when the next dose is near the hour, do not take the missed dose. You should not take two doses of the medicine together because of the missed dose

 

Contraindications to posaconazole

  • Note the expiration date of posaconazole and do not take it if your medicine has expired.
  • Never give posaconazole to another person, even if you have the same symptoms.
  • Check for drug interactions with posaconazole, and if you are using a drug that interacts with this drug, talk to your doctor about using your medications.

 

Posaconazole during pregnancy and lactation

During pregnancy and lactation, you should not use the drug arbitrarily without consulting your doctor. Medications can have devastating effects on the fetus or on yourself.

 

The effect of posaconazole on driving and working with machines

Posaconazole can make you drowsy, so make sure you are alert before driving or operating machinery.

 

 Posaconazole drug interactions

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Posaconazole affects the performance of some drugs, including: specific benzodiazepines (midazolam), alpha-blockers (such as alfuzosin, silodosin, tamsulosin), ergot alkaloids (such as dihydro ergotamine), ergot for heart, ergot (Such as disopyramide (disopyramide), drondarone, quinidine), lovazidone, rivaroxaban, pimozide, ranolazine, sirolimus, some cholesterol "statin" drugs (such as lovastatin, simvastatin).

Drugs that can affect the removal of posaconazole from the body and affect its function include: efavirenz, rifamycins (such as rifabutin, rifampin), anticonvulsants (such as carbamazepine, phenobarbital).

 

Special warnings and precautions while taking posaconazole

Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best to let your doctor know the following before taking this medicine:

  • If you are pregnant or planning to become pregnant or breast-feeding your baby.
  • If you have any liver problems.
  • If you have a heart problem or arrhythmia.
  • If you have a blood disorder called porphyria.
  • If you are taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor's prescription, such as herbal medicines and complementary medicines.
  • If you have a history of an allergic reaction to a drug.

 

Side effects of posaconazole

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking the medicine. In case of persistent side effects, the physician should be informed.

  • Dizziness and drowsiness: Avoid driving and working with tools in these situations.
  • Headache, fever, pruritus ani and infection
  • Dry mouth
  • Feeling sick, indigestion, nausea and heartburn
  • Diarrhea: Drink plenty of fluids.
  • Weakness and confusion (change in blood electrolytes): Tell your doctor if any of these things bother you.

Consult your doctor if you have any other symptoms that you feel may be due to posaconazole.

 

Overdose of posaconazole (drug poisoning)

Do not take more than the dose prescribed by your doctor.

If you feel that someone has been poisoned and you have symptoms such as shortness of breath, fainting and weakness (fainting), call the emergency room immediately.

 

Storage conditions of posaconazole

Keep the medicine out of the reach of children.

Store the medicine in a cool, dry place away from heat and direct sunlight.

You can store the liquid medicine bottle only 4 weeks after opening.

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