General English name: Tiagabine

Brand: Gabitril

Application: Epilepsy with seizures in adults or children over 12 years







Thiagabine Drug Information

Contraindications Thiagabine

Drug Interaction Thiagabine

Tips to consider before taking thiagabine

Possible side effects of thiagabine

How to store thiagabine







Thiagabine Drug Information

Medication Information: Epilepsy means that a person often has fainting and seizures. Seizure is a transient condition caused by electrical changes in the brain. In mild seizures (localized seizures), electrical changes occur in a specific part of the brain and therefore a localized part of the body has seizures. Because different parts of the body are controlled by different parts of the brain.

The symptoms seen in mild seizures depend on which part of the brain has undergone electrical changes. Mild seizures can sometimes turn into generalized seizures that affect the whole body. This condition is called secondary seizures and may involve muscles, behavior, alertness, or a combination of these.

Appropriate antiepileptic drugs can prevent these symptoms. Thiagabine is used in combination with other drugs to balance the electrical activity of the brain. This is done by increasing a chemical in the brain called gamma aminobutyric acid (GABA). This mechanism of action of thiagabine helps prevent seizures.


Contraindications Thiagabine

Pay attention to the expiration date of the medicine and do not take it if the medicine in your hand has expired.

Never give the medicine to anyone else, even if you have the same symptoms.

• Do not take more than the dose prescribed by your doctor.

Check for drug interactions and be sure to tell your doctor what other medications you are taking.


Drug Interaction Thiagabine

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some medications that may interact with thiagabine include some recreational and street drugs such as methamphetamine "speed" or MDMA "ecstasy".

Some medications increase the risk of seizures and cause anticonvulsant drugs, such as thiagabine, to not work well. Tell your doctor if you are taking medicines such as isoniazid, antipsychotics (for example, phenothiazines such as chlorpromazine) or alcohol that interfere with thiagabine function.

If you are taking medicines that cause drowsiness, tell your doctor or pharmacist, including: alcohol, antihistamines (such as cetirizine, diphenhydramine), sleeping pills or anti-anxiety medications (such as alprazolam), alprazolam (alprazolam) Diazepam, zolpidem, muscle relaxants, analgesics and analgesics (such as codeine), and tricyclic antidepressants (eg, imipramine or amitriptyline).

Check the labels on all your medications (such as allergies or colds and cough medicines) as most of their ingredients cause drowsiness. Ask your doctor or pharmacist about taking these medicines.


Tips to consider before taking thiagabine

Some medications can not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed. Therefore, it is best for your doctor to be aware of the following before taking thiagabine:

• If you are pregnant or planning to become pregnant, or if you are breast-feeding.

• If you have liver problems.

• If you have porphyria blood disease.

• If you are currently taking certain medications. These include all available medicines, whether prescribed or used by your doctor, such as herbal medicines and supplements.

• If you have ever been allergic to a particular medicine.


Possible side effects of thiagabine

All drugs, in addition to their positive effects, can cause unwanted side effects in the body. However, these complications do not occur in all people. Over time, your body will adjust to the new medicine and these symptoms will go away, but if the following symptoms persist or become painful, consult your doctor.

Out of every 10 patients taking thiagabine, more than one person may experience the following side effects:

Dizziness, tremors, fatigue, and anger: Talk to your doctor if any of these occur.

Feeling bored: Eat simple meals and avoid high-fat and spicy foods.

Usually, less than one in 10 patients taking thiagabine may experience the following side effects:

Gastrointestinal upset, diarrhea: Eat simple foods and drink plenty of water daily.

Blurred vision: Avoid driving and working with tools. Tell your doctor if this continues.

Decentralization, mood swings, sleep problems, speech problems, sudden muscle tremors: Consult your doctor if any of the above are annoying.

Important Note: Your doctor will talk to you about less common but serious side effects of the medication. Although these symptoms are rare in people, tell your doctor if you notice any of these symptoms:

  • Skin rashes
  • Unusual blisters

Talk to your doctor if you have any other symptoms that you feel may be due to thiagabine.


How to store thiagabine

• Keep all medicines out of the reach of children.

• Keep the medicine in a cool, dry place away from heat and direct sunlight.

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