Ulipristal acetate
Brand: Esmya
Application: Fibroids in the uterus
Pharmacological information of olipristal acetate
Contraindications to the use of olipristal acetate
Drug interaction of olipristal acetate
Tips to consider before taking olipristal acetate
Possible side effects of olipristal acetate
How to store olipristal acetate
Pharmacological information of olipristal acetate
Drug Information: Uterine fibroids (myomas) are the growth of non-cancerous masses in the uterus. They can sometimes cause heavy or painful periods, bloating, and urinary problems. Surgery is the most common treatment for fibroids with symptoms. Olipristal acetate is prescribed to reduce fibroid volume before surgery.
The hormone progesterone in women plays an important role in the development of fibroids. Olipristal acetate blocks the effects of the female hormone progesterone, so fibroids stop growing and remain small.
Olipristal acetate is sold in two brands and contains different amounts and uses. The low-dose pill (brand name Esmya contains 5 mg of olipristal acetate) is used to treat severe and painful periods of uterine fibroids. The higher-powered pill of olipristal acetate (brand EllaOne), which is called an emergency contraceptive, will be discussed in a separate article.
Contraindications to the use of olipristal acetate
- Note the expiration date of the olipristal acetate medicine and do not take it if the medicine in your hand has expired.
- Never give the medicine to anyone else, even if you have the same symptoms.
- Do not take more olipristal acetate than the dose prescribed by your doctor.
- Check for olipristal acetate drug interactions and be sure to tell your doctor what other medications you are taking.
Drug interaction of olipristal acetate
Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter medicines and herbal products) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.
Other drugs can affect the removal of olipristal acetate from the body and alter its function. These drugs include: azole antifungals (such as itraconazole, ketoconazole), griseofulvin, modafinil, rifamycins (such as rifampin, rifabutin, Dar) Anticonvulsants (such as barbiturates, carbamazepine, phlebamate, phenytoin, primidone, topiramate), HIV medications (such as nelfinavir, noirapine, ritonavir).
Tips to consider before taking olipristal acetate
Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to know the following before taking olipristal acetate:
- If you are pregnant or breastfeeding.
- If you have severe asthma.
- If you have any liver or kidney problems.
- If you have cancers such as breast, uterine, cervical or ovarian cancers.
- If you are currently taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor's prescription, such as herbal medicines and complementary medicines.
- If you have a history of an allergic reaction to a drug.
Possible side effects of olipristal acetate
All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away after a short time of taking the medicine. In case of persistent side effects, the physician should be informed.
Complications are very common
- Failure to menstruate during treatment with this drug and a few weeks later, thickening of the uterine wall
Common complications
Headache, Other pain, Dizziness and fatigue, Feeling sick, Abdominal pain, Pimples, Weight gain, Breast tenderness, Flushing
Consult your doctor if you have any other symptoms that you feel are due to the use of this medicine.
How to store olipristal acetate
- Keep all medicines out of the reach of children.
- Keep the medicine in a cool, dry place away from heat and direct sunlight.