what are the possible causes of bipolar disorder


Bipolarity is a disease and a multifactorial disorder.

Although medical studies have not yet been able to determine the definitive cause of bipolarity, they have been able to identify some people who are at risk for the disease.

Recognizing the causes and possible risk factors that increase the incidence of the disease provides the conditions that in a large population of people, we can prevent the infection of new people through the necessary follow-up and interventions, and reduce the progression and severity of discomfort by starting treatment early and timely.

In the following we will talk more about a list of common causes for bipolar disorder.

What are possible causes of bipolar disorders?


Causes of bipolarity disorder

Bipolar epidemiology

What are the underlying causes of neurotransmitter imbalance in patients with bipolar disorder?

bipolarity triggers



Causes of bipolarity disorder:

Doctors say that what causes the signs and symptoms in people with bipolar disorder is:


  • chemical imbalance in the brain:

In the human brain, a number of substances are produced and secreted that doctors call them neurotransmitters.

There are many neurotransmitters in the human brain, each of which is responsible for controlling or coordinating some of the activity of your brain and nerve cells.

In the brain of people with bipolar disorder, the balance of production and secretion of certain neurotransmitters is disturbed.

It is this imbalance in neurotransmitters that is the main cause of the signs and symptoms.

But what are the causes that can cause this neurotransmitter imbalance?

What factors do doctors consider as triggering the onset of signs and symptoms of bipolar disorder?

Episodes of depression and mania will be the hallmarks of bipolar disorder.

Mood swings in affected individuals are different from normal and non-physiological mood swings.

People in periods of depression, especially mania, have manifestations and behaviors that facilitate diagnosis.

Bipolar disorder is a lifelong disorder, but it is now well controlled so that the affected person can live, and work with the community.


Bipolar epidemiology:

  • Bipolar spectrum prevalence in the general population is about 4.2%
  • Bipolar type I prevalence in the general population is about 0.6%
  • Bipolar type II prevalence in the general population is about 0.4%

The above studies were based on statistics obtained from eleven countries.


  • It is more common in urban populations than rural ones.
  • It has a high prevalence in institutionalized (such as sanatoriums and prisons).
  • Some studies have found the prevalence to be higher in less educated populations.
  • The peak age of infection is between fifteen to nineteen years and twenty to twenty-four years.
  • People with a first-degree relative with bipolar disorder are 11 percent more likely to be infected than the general population, so genetics are likely to play an important role.


About four percent of the total population has type 1 and type 2 bipolar disorder.

Cyclothymia affects about 2.4% of the general population.

Major depression is four times more common than bipolar disorder.


About one percent of high school students have bipolar disorder. About half to one percent of adult adults have bipolar disorder, young people are at least three times more likely to have bipolar disorder than adults.


What are the underlying causes of neurotransmitter imbalance in patients with bipolar disorder?

Underlying causes of neurotransmitter imbalance in patients with bipolar disorder include:


  • Genetic:

It seems that the presence of bipolarity in one nation and family confirms the genetic background of this disorder.

People with first-degree relatives are more likely to be at risk.

However, a specific gene for bipolar transmission is not yet known in an ethnic group, but physicians know that in order for a genetic predisposition to be detected, favorable environmental conditions are necessary, the environmental stimulus is called the triggering agent.


Bipolar triggers:

Stressful situations are known as the most important and main triggering factor:

    • Mental abuse, physical or sexual
    • Death of loved ones
    • The failure of an emotional relationship
    • Physical diseases
    • Sleep disorders
    • Complex financial problems
    • Occupational problems
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